Disease of the Thyroid Gland: A Histopathological Perspective

Emmanuel, Innocent and Aliyu, Mansur Ramalan and Ochigbo, Adam and Akpa, Philip and Mandong, Jagshak Barnabas and Mandong, Barnabas Mafala (2019) Disease of the Thyroid Gland: A Histopathological Perspective. Asian Journal of Research and Reports in Endocrinology, 1 (1). pp. 32-40.

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Abstract

The thyroid is affected primarily by disease conditions which are variously classified and are not uncommon worldwide. They could lead to enlargement of the thyroid gland thereby earning the designation “goiter”. Globally, iodine deficiency has been identified as a major cause of goiter. This was a descriptive retrospective study of consecutive cases of thyroid specimen analyzed at the Histopathology Department of the Jos University Teaching Hospital, Jos, Nigeria, between January 2008 and December 2017. The aim of this work is to study thyroid disorders histologically, relating these findings to age and sex, and comparing same with previous reports.

The Hospital’s Medical records and the Histopathology Departments served as sources for extraction of patient’s data which included age, sex, and histological diagnosis. Archival slides were reviewed to confirm the diagnosis of the thyroid lesion.

Three hundred and eleven (311) cases of thyroid disease were diagnosed histologically at the Jos University Teaching Hospital during the study period. These lesions were broadly classified into developmental anomalies, hyperplasias, immune/inflammatory diseases, and neoplasm. They accounted for 1.9% (6 cases), 81.3% (253 cases), 3.9% (12 cases), and 12.9% (40 cases) of all cases respectively. The age range of the study population was 1 year to 70 years, with a mean age of 41.2±12.0 SD, and peak incidence at 30 years to 39 years. There were 25 males and 286 females making a male female (M/F) ratio of 1:10.2.

Thyroid disorders are essentially a female disease in our environment occurring commonly in the third and fourth decade of life.

Item Type: Article
Subjects: STM One > Medical Science
Depositing User: Unnamed user with email support@stmone.org
Date Deposited: 04 Jul 2023 05:03
Last Modified: 17 May 2024 10:34
URI: http://publications.openuniversitystm.com/id/eprint/1501

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