The Antibacterial Potency of Alkaloid and Saponin Extracts from Solanum macrocapon (Garden Egg)

The antibacterial potency and efficacy of alkaloid and saponin extracts from Solanum macrocapon (Garden egg) were investigated. The susceptibility of bacteria strains viz were Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa against the two extracts was determined using disk diffusion methods with different concentration (10 – 0.625 mg/mL). All the bacteria were susceptible to both alkaloid and saponin with different ranges of zone of inhibition at concentration of 10 mg/mL. The susceptibility of the bacteria to alkaloid with zone of inhibition for Escherichia coli (14.00 mm), Staphylococcus aureus (12.00 mm), Pseudomonas aeruginosa (10.00 mm) and susceptibility of the organisms to saponins with zone of inhibition for Pseudomonas aeruginosa (21.00 mm), Staphylococcus aureus (12.00 mm) and Escherichia coli (10.00 mm). The minimum inhibitory concentration (MIC) of the alkaloid and saponins crude extracts were observed at 1.25 mg/mL respectively. The most susceptible bacteria to saponin and alkaloid were Pseudomonas aeruginosa and Escherichia coli respectively.